• Patchliner

  • Patchliner

  • Patchliner

  • Dynamite8

    Automated Dynamic Clamp
  • Patchliner


Kir channels - Rapid external solution exchange study in RBL cells

icon pl   Patchliner data and applications:application16 kir2 2 small

The basophilic leucaemia cells (RBL) exhibit an inwardly rectifying potassium current, Kir. Changing the external K+ concentration (here between 4.5 mM and 143 mM) leads to a change of the current amplitude of the inward current (holding: -100 mV). This gives us a convenient tool to study the speed of the external solution exchange which was determined as ~50 ms.



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